When science fiction becomes science fact – AI for rare disease diagnosis
The latest edition of The Biopôle Review, published by Biopôle Lausanne, explores the relationship between science fiction and real-world scientific innovation – and features Volv Global as one of the companies on the Biopôle campus whose work now occupies territory that imagination once claimed exclusively. The full article is available on the Biopôle website: Has science fiction inspired the scientific innovations of today?
The Biopôle Review traces the journey from canonical science fiction – Huxley’s Brave New World, Asimov’s I, Robot, Gibson’s Neuromancer, the regenerative medicine of Star Trek – to the operational realities now being developed on the Biopôle campus. It surveys five domains: genetics and cell therapy, autonomous machines and AI, brain-computer interfaces and implants, regenerative medicine, and synthetic biology. For each, it profiles companies whose work has moved from the realm of the imaginable to the demonstrably real.
The article’s central argument is that science and science fiction engage in a continuous, reciprocal exchange – each expanding what the other believes is possible. It is a compelling frame for the kind of work being done at Biopôle, where ambition and scientific rigour sit side by side. Volv Global is featured within the AI section of the piece, and the placement reflects a genuine alignment between the article’s central argument and the work we do.
The most persistent gap in healthcare for patients living with rare or difficult-to-diagnose diseases is not a shortage of treatments. It is the failure to identify the right patients in the first place – and to identify them early enough for any intervention to make a meaningful difference. This is the problem our machine learning methodology was built to address.
We learn the pattern of a disease from labelled data – the cases that have been identified and documented – and then apply that understanding to population-scale real-world data where no such labels exist. The patients we surface are the ones who have been missed: individuals whose records carry no diagnostic code for the condition they have, but whose data, examined at the right scale and with the right methodology, reveals the signal. These are the undiagnosed and the misdiagnosed – people who may have spent years, sometimes decades, navigating a healthcare system that has not yet found the right answer for them. We detect them earlier than conventional approaches, and with a precision that population-scale analysis makes possible.
The consequences of finding these patients earlier are significant at every level. For the individual, it means access to appropriate care sooner. For pharmaceutical companies, it means a truer picture of the patient population – with direct implications for clinical development strategy, trial design, endpoint selection, and real-world evidence generation. For health systems, it means a reduction in the cost burden of prolonged, misdirected diagnostic journeys.
We work across more than 400 million patient records, held by trusted data partners in the UK, US, Germany, the Netherlands, and beyond – always anonymised, always privacy-first. Our work spans rare diseases, difficult-to-diagnose conditions, and diseases where significant care gaps persist despite relatively high prevalence.
Tech Tour Growth Health is one of Europe's most established gatherings at the intersection of…
Volv Global is pleased to be participating in the Life Sciences Innovation & Investment Corridor…
The ISPOR International Annual Conference 2026 brings together global leaders in health economics and outcomes…
By Léon Van Wouwe, Clinical Innovation Director, Volv Global Inflammatory Bowel Disease (IBD) management has…
Introduction Advocacy plays a critical role in accelerating progress in rare diseases. As technology advances,…
As our commemoration of Rare Disease Day 2026, we are pleased to present a guest…